产品展厅
产品展厅
重组蛋白相关产品
重组蛋白是指利用DNA重组技术生产的蛋白质。重组蛋白可弥补体内功能蛋白缺陷，或者增加体内蛋白功能，达到治疗疾病目的，药物是重组蛋白发展的重要方向，在部分疾病治疗领域具有不可替代的重要作用。用于重组蛋白生产的宿主细胞可以来自细菌、哺乳动物细胞、昆虫和酵母。汇智泰康致力于为客户提供各种高纯度、低成本活性重组蛋白，包括细胞因子、生长因子、CD分子、免疫检查点等等。
产品应用：
|
? 免疫检查点 |
? 抗体药物靶点 |
|
? CAR-T细胞治疗靶点 |
? Fc受体 |
|
? 疫苗研发 |
? 细胞因子 |
产品优势：
|
? 高活性、高纯度 |
? 低成本 |
|
? 不同的大小，种类和标签 |
? 货期短 |
产品类别：
7.2.1. 细胞因子(cytokine，CK)
是由多种组织细胞(主要为免疫细胞)所合成和分泌的小分子多肽或糖蛋白。细胞因子能介导细胞间的相互作用，具有多种生物学功能，如调节细胞生长、分化成熟、功能维持、调节免疫应答、参与炎症反应、创伤愈合和肿瘤消长等。
|
货号 |
名称 |
标签 |
规格 |
|
071A011 |
Recombinant human IL-2 |
His Tag |
100μg |
|
071A012 |
Recombinant human IL-3 |
His Tag |
25μg |
|
071A021 |
Recombinant human IL-4 |
His Tag |
100μg |
|
071A022 |
Recombinant human IL-4 |
His Tag |
25μg |
|
071A023 |
Recombinant human IL-4 |
human Fc |
100μg |
|
071A024 |
Recombinant human IL-4 |
human Fc |
25μg |
|
071A025 |
Recombinant human IL-4 |
mouse Fc |
100μg |
|
071A026 |
Recombinant human IL-4 |
mouse Fc |
25μg |
|
071A031 |
Recombinant human IL-6 |
His Tag |
100μg |
|
071A032 |
Recombinant human IL-6 |
His Tag |
25μg |
|
071A033 |
Recombinant human IL-6 |
human Fc |
100μg |
|
071A034 |
Recombinant human IL-6 |
human Fc |
25μg |
|
071A041 |
Recombinant human IL-13 |
His Tag |
100μg |
|
071A042 |
Recombinant human IL-13 |
His Tag |
25μg |
|
071A051 |
Recombinant human IL-17A |
His Tag |
100μg |
|
071A052 |
Recombinant human IL-17A |
His Tag |
25μg |
|
071A053 |
Recombinant human IL-17A |
human Fc |
100μg |
|
071A054 |
Recombinant human IL-17A |
human Fc |
25μg |
|
071A055 |
Recombinant human IL-17A |
mouse Fc |
100μg |
|
071A056 |
Recombinant human IL-17A |
mouse Fc |
25μg |
|
071A061 |
Recombinant human TSLP |
His Tag |
100μg |
|
071A062 |
Recombinant human TSLP |
His Tag |
25μg |
|
071A063 |
Recombinant human TSLP |
human Fc |
100μg |
|
071A064 |
Recombinant human TSLP |
human Fc |
25μg |
|
071A065 |
Recombinant human TSLP |
mouse Fc |
100μg |
|
071A066 |
Recombinant human TSLP |
mouse Fc |
25μg |
|
071A071 |
Recombinant human IL-6R |
His Tag |
100μg |
|
071A072 |
Recombinant human IL-6R |
His Tag |
25μg |
|
071A073 |
Recombinant human IL-6R |
human Fc |
100μg |
|
071A074 |
Recombinant human IL-6R |
human Fc |
25μg |
|
071A075 |
Recombinant human IL-6R |
mouse Fc |
100μg |
|
071A076 |
Recombinant human IL-6R |
mouse Fc |
25μg |
|
071A081 |
Recombinant human IL-4R |
His Tag |
100μg |
|
071A082 |
Recombinant human IL-4R |
His Tag |
25μg |
|
071A083 |
Recombinant human IL-4R |
human Fc |
100μg |
|
071A084 |
Recombinant human IL-4R |
human Fc |
25μg |
|
071A085 |
Recombinant human IL-4R |
mouse Fc |
100μg |
|
071A086 |
Recombinant human IL-4R |
mouse Fc |
25μg |
|
071A091 |
Recombinant human IL7R |
His Tag |
100μg |
|
071A092 |
Recombinant human IL7R |
His Tag |
25μg |
|
071A093 |
Recombinant human IL7R |
human Fc |
100μg |
|
071A094 |
Recombinant human IL7R |
human Fc |
25μg |
|
071A095 |
Recombinant human IL7R |
mouse Fc |
100μg |
|
071A096 |
Recombinant human IL7R |
mouse Fc |
25μg |
|
071A101 |
Recombinant human IL-17RA |
His Tag |
100μg |
|
071A102 |
Recombinant human IL-17RA |
His Tag |
25μg |
|
071A111 |
Recombinant human TSLPR |
His Tag |
100μg |
|
071A112 |
Recombinant human TSLPR |
His Tag |
25μg |
7.2.2. 生长因子（growth factor）
是 一类通过与特异的、高亲和的细胞膜受体结合，调节细胞生长与其他细胞功能等多效应的多肽类物质。其是由多种细胞分泌，作用于特定的靶细胞，调节细胞分裂、基质合成与组织分化的细胞因子。有胰岛素、表皮生长因子（EGF）、成纤细胞生长因子（fibroblast growth factor，FGF）、血小板来源增殖因子（platelet－derived growth factor，PDGF）以及生长激素释放抑制因子（somatostatin=SRIH）等。
|
货号 |
名称 |
标签 |
规格 |
|
072A011 |
Recombinant human VEGF |
His Tag |
100μg |
|
072A012 |
Recombinant human VEGF |
His Tag |
25μg |
|
072A013 |
Recombinant human VEGF |
human Fc |
100μg |
|
072A014 |
Recombinant human VEGF |
human Fc |
25μg |
|
072A015 |
Recombinant human VEGF |
mouse Fc |
100μg |
|
072A016 |
Recombinant human VEGF |
mouse Fc |
25μg |
|
072A021 |
Recombinant human VEGFR |
His Tag |
100μg |
|
072A022 |
Recombinant human VEGFR |
His Tag |
25μg |
|
072A023 |
Recombinant human VEGFR |
human Fc |
100μg |
|
072A024 |
Recombinant human VEGFR |
human Fc |
25μg |
|
072A025 |
Recombinant human VEGFR |
mouse Fc |
100μg |
|
072A026 |
Recombinant human VEGFR |
mouse Fc |
25μg |
7.2.3. CD分子
是不同谱系的白细胞在正常分化成熟的不同阶段及活化过程中，出现或消失的细胞表面标记。它们是细胞膜上的一类蛋白质或糖蛋白。在生理学上，CD分子有许多用途，通常用作细胞的重要受体或配体。 不仅可作为表面标志用于细胞的鉴定和分离，还广泛参与细胞的生长、成熟、分化、发育、迁移、激活。
|
货号 |
名称 |
标签 |
规格 |
|
073A011 |
Recombinant human CD3 |
His Tag |
100μg |
|
073A012 |
Recombinant human CD3 |
His Tag |
25μg |
|
073A021 |
Recombinant human CD4 |
His Tag |
100μg |
|
073A022 |
Recombinant human CD4 |
His Tag |
25μg |
|
073A031 |
Recombinant human CD8 |
His Tag |
100μg |
|
073A032 |
Recombinant human CD8 |
His Tag |
25μg |
|
073A041 |
Recombinant human CD11 |
His Tag |
100μg |
|
073A042 |
Recombinant human CD11 |
His Tag |
25μg |
|
073A051 |
Recombinant human CD19 |
His Tag |
100μg |
|
073A052 |
Recombinant human CD19 |
His Tag |
25μg |
|
073A061 |
Recombinant human CD34 |
His Tag |
100μg |
|
073A062 |
Recombinant human CD34 |
His Tag |
25μg |
|
073A071 |
Recombinant human CD45 |
His Tag |
100μg |
|
073A072 |
Recombinant human CD45 |
His Tag |
25μg |
|
073A081 |
Recombinant human CD56 |
His Tag |
100μg |
|
073A082 |
Recombinant human CD56 |
His Tag |
25μg |
|
073A091 |
Recombinant human CD138 |
His Tag |
100μg |
|
073A092 |
Recombinant human CD138 |
His Tag |
25μg |
|
073A101 |
Recombinant human CD271 |
His Tag |
100μg |
|
073A102 |
Recombinant human CD271 |
His Tag |
25μg |
|
073B111 |
Recombinant mouse CD3 |
His Tag |
100μg |
|
073B112 |
Recombinant mouse CD3 |
His Tag |
25μg |
|
073B121 |
Recombinant mouse CD4 |
His Tag |
100μg |
|
073B122 |
Recombinant mouse CD4 |
His Tag |
25μg |
|
073B131 |
Recombinant mouse CD8 |
His Tag |
100μg |
|
073B132 |
Recombinant mouse CD8 |
His Tag |
25μg |
|
073B141 |
Recombinant mouse CD11B |
His Tag |
100μg |
|
073B142 |
Recombinant mouse CD11B |
His Tag |
25μg |
|
073B151 |
Recombinant mouse CD11C |
His Tag |
100μg |
|
073B152 |
Recombinant mouse CD11C |
His Tag |
25μg |
|
073B161 |
Recombinant mouse CD19 |
His Tag |
100μg |
|
073B162 |
Recombinant mouse CD19 |
His Tag |
25μg |
|
073B171 |
Recombinant mouse CD25 |
His Tag |
100μg |
|
073B172 |
Recombinant mouse CD25 |
His Tag |
25μg |
|
073B181 |
Recombinant mouse CD45 |
His Tag |
100μg |
|
073B182 |
Recombinant mouse CD45 |
His Tag |
25μg |
|
073B191 |
Recombinant mouse CD117 |
His Tag |
100μg |
|
073B192 |
Recombinant mouse CD117 |
His Tag |
25μg |
7.2.4. 免疫检查点
一些存在人体免疫系统的共刺激和共抑制分子、蛋白，它们会传递信号；共刺激分子受体会提高机体的免疫反应用来对抗病原体，抑制性分子受体能够负向调节T细胞活力，用来保护过度的炎症反应。它们是癌症治疗中很值得关注的靶点，比如PD-1、PD-L1、B7、CD28、TIM、CD226家族。
重组蛋白表达系统分为原核表达和真核表达系统。原核表达主要是大肠杆菌表达系统，真核生物表达系统主要有酵母菌、哺乳动物细胞、昆虫细胞等表达系统。
|
货号 |
名称 |
标签 |
规格 |
|
074A011 |
Recombinant human PD-1 |
His Tag |
100μg |
|
074A012 |
Recombinant human PD-1 |
His Tag |
25μg |
|
074A013 |
Recombinant human PD-1 |
human Fc |
100μg |
|
074A014 |
Recombinant human PD-1 |
human Fc |
25μg |
|
074A015 |
Recombinant human PD-1 |
mouse Fc |
100μg |
|
074A016 |
Recombinant human PD-1 |
mouse Fc |
25μg |
|
074A021 |
Recombinant human PD-L1 |
His Tag |
100μg |
|
074A022 |
Recombinant human PD-L1 |
His Tag |
25μg |
|
074A023 |
Recombinant human PD-L1 |
human Fc |
100μg |
|
074A024 |
Recombinant human PD-L1 |
human Fc |
25μg |
|
074A025 |
Recombinant human PD-L1 |
mouse Fc |
100μg |
|
074A026 |
Recombinant human PD-L1 |
mouse Fc |
25μg |
|
074A031 |
Recombinant human B7H3 |
His Tag |
100μg |
|
074A032 |
Recombinant human B7H3 |
His Tag |
25μg |
|
074A033 |
Recombinant human B7H3 |
human Fc |
100μg |
|
074A034 |
Recombinant human B7H3 |
human Fc |
25μg |
|
074A035 |
Recombinant human B7H3 |
mouse Fc |
100μg |
|
074A036 |
Recombinant human B7H3 |
mouse Fc |
25μg |
7.2.5. SARS-cov2 相关蛋白
*病毒由双层脂质的囊膜组成，包含刺突蛋白（Spike protein，S）、包膜蛋白（Envelope protein，E）、膜蛋白（Membrane protein，M）以及核衣壳蛋白（Nucleoc-apsid protein，N）。其中S蛋白和N蛋白是其中最重要的用于检测的靶点蛋白。N蛋白一般种属特异性较高，通常作为检测的靶点，而表面的S蛋白特异性会低一些。S蛋白含有两个亚基，S1和S2，其中S1主要包含有受体结合区（receptor binding domain，RBD），负责识别细胞的受体，S2含有膜融合过程所需的基本元件。*病毒是通过识别ACE2蛋白进入人体细胞的。ACE2就像是“门把手”，病毒抓住它，从而打开了进入人体细胞的大门。
|
货号 |
名称 |
标签 |
规格 |
|
075A011 |
S1 |
His Tag |
100μg |
|
075A012 |
S1 |
His Tag |
25μg |
|
075A021 |
ACE2 |
His Tag |
100μg |
|
075A022 |
ACE2 |
His Tag |
25μg |
|
075A031 |
RBD |
His Tag |
100μg |
|
075A032 |
RBD |
His Tag |
25μg |
